green_thumb:
You asked "...will virus protection software run on it (ME) if the system requirements do not specify that it supports windows ME?". The answer is no. Find an anti-virus program that stills lists Win ME as one of the supported operating systems.
It's at least a six year old system (using 2001 technology?), so its probably not the bigest badest fastest system around. On top of that, WinMe and the other Win9x operating systems are limited by "system resources (user and GDI)" not memory. The system designers only allowed a fixed amount of buffer space to support windows displays and dialog boxes. If these dip too low, as they will if you're running too many programs concurrently, your system will hang. The WinNT line (WinNT, Win2000, WinXP) and Vista do not have this limitation. You want an anti-virus program that is light on system resources and designed to be compatible with Win9x/WinME.
If the system is for your personal home non-commercial use the following "free" versions will work well on your system:
o AVG Free Edition 7.5 Build 488a1157
o Avast! Home Edition 4.7.1043
o ClamWin Free Antivirus 0.91.2 (file scanner only, but free for all uses)
The first one "AVG Anti-Virus Free Edition" was also recommended by Broni and is a popular choice for older Windows operating systems.
You can find links to all three and many others in the Anti-Virus section of the "MajorGeeks" download web site:
http://www.majorgeeks.com/downloads29.htmlYou didn't say what kind of system you have; how you wish to use it (personal or commercial); or whether it will be connected to the internet either directly or indirectly. If you're going to access the internet from that system you should add some protection against adware, malware, spyware, trojans, and any other bad boys you can think of. This protection should also include a firewall. I prefer separate programs for anti-virus, anti-malware, and firewall protection. I subscribe to the theory that no one software company is going to be the best in all three categories; so I prefer separate programs for each category rather than an integrated security suite. But you only asked about anti-virus...