I'm in Derby (check my profile).
I use Overclockers for my supplier, they do a lot of prebuilt systems (which are fully configurable if you call them)and components too. Customer service is fantastic, I usually go and collect my orders because I'm not too far from them. 40 minute drive = £10 of petrol, vs. at least £5 for delivery and having to wait.
No, I don't work for them, heh.
Anyway, a quick build I just threw together from there:
Q8200 CPUHD4870 graphics cardEP45-DS3P motherboardBarracuda 7200.12 1TB HDDPC P&C 610W PSUAntec 300 caseOCUK 4GB 800MHz RAMPioneer DVDRW driveXP Home£636.71 including delivery.
That's easily configurable and upgradeable, or downgradeable. Changing to Vista Basic would be the same price, Home Premium adds another £15.
There's a 512MB version of that graphics card for a little cheaper which is fine for lower resolution gaming, or if you're not a hardcore gamer you could drop to a 4850, 4830, or 4770 for up to £30 less. A 9600GSO would be quite a bit cheaper and would be fine for lower end gaming.
For the RAM, you may want to change that for something with a better warranty -
this kit is on offer and is pretty good for an extra £8 with a lifetime warranty.
Those are just some examples of how you could change it anyway, you know better than me what you want.
Hope this helps.