longshinshen,
you need to provide more information about your hardware. Otherwise people who want to help you have to guess at your problem. When you hear the USB disconnect sound over and over again it almost always means there is some type of hardware issue and seldom a problem with software.
Are you using a laptop computer? What brand? Model? And how old is it? Has this problem ever occurred before?
Also, are you using a mouse with a laptop? Why? Laptops usually have some other type of input device other than a mouse. What kind of mouse to you have? Do you have another mouse you can try?
Also, are you connecting to the Internet through a Wi-Fi card that is built into the laptop? Have you noticed any difficulty with your Wi-Fi connection?
There are documented cases where a mouse will not work properly with a Wi-Fi connection present. But that is so rare and bizarre that we would not assume that unless you provided us the specific details that would lead to that conclusion.
So please, please give specific details about what kind of laptop you are running and what kind of mouse you have. For example, if you're using a wireless mouse you can have a conflict between your Wi-Fi and the wireless mouse. Rare, but it does happen. But without the details about your hardware everybody is just guessing.
I would suggest you try disconnecting the mouse altogether and using the pointing device that's built into the laptop and see if that makes any difference.
EDIT: Just now saw yu said it is a desktop. Still, it would be nice to know what model? Does it use USB 3.0? The USB 3.0 has an issue with Wi-Fi in 2.5 GHz.
Can you use Ethernet to connect to the router? Do you have another mouse?
References:
Google USB 3.0 and Wi-Fi interference