Here's the fix if you havn't already found out. I had the same problem when trying to play the Aveyond games.
The problem was that I had DEP (Data Execution Protection) enabled. For whatever reason, the error message gave me the AppCrash error above instead of the standard message about "DEP has closed the program."
To solve the problem, I added the application to the DEP exclusion list and everything worked again.
To change your DEP list do the following:
1. Open System by clicking the Start button Picture of the Start button, clicking Control Panel, clicking System and Maintenance, and then clicking System.
2. Click Advanced System Settings. Administrator permission required If you are prompted for an administrator password or confirmation, type the password or provide confirmation.
3. Under Performance, click Settings.
4. Click the Data Execution Prevention tab, and then click Turn on DEP for all programs and services except those I select.
4. now browse to your game that is not working because of RGSS error msg and closing without solution. For example mine was aveyond.exe
done.. game works again :-) You might have to reboot