I think I have a PUP/virus on this drive.

[SuperDave]

I'd like to scan your machine with ESET OnlineScan

•Hold down Control and click on the following link to open ESET OnlineScan in a new window.
ESET OnlineScan

•Click the button.
•For alternate browsers only: (Microsoft Internet Explorer users can skip these steps)

• Click on to download the ESET Smart Installer. Save it to your desktop.
  
• Double click on the icon on your desktop.
  

•Check
•Click the button.
•Accept any security warnings from your browser.

• Leave the check mark next to Remove found threats.
  

•Check
•Push the Start button.
•ESET will then download updates for itself, install itself, and begin scanning your computer. Please be patient as this can take some time.
•When the scan completes, push
•Push , and save the file to your desktop using a unique name, such as ESETScan. Include the contents of this report in your next reply.
•Push the button.
•Push
A log file will be saved here: C:\Program Files\ESET\ESET Online Scanner\log.txt

[ImnoGuru]

SuperDave I ran the ESET scanner but lost my internet during the first run.
So I closed it off and it must have followed its closedown settings and deleted the potential threats (7 found).
So I ran it again and after 7 hrs it finished.

I had a look for the log files but cant find anything.
My settings didnt have facility to set where the downloads were to be sent, just the 2 tick boxes then advanced settings.

I went to program files ESET and then into log but it was empty?

Anyway, an update to performance and hijacking occurrences.
My webpages have come back to (normal?) what I've been used to seeing and the unexpected opening of ads in new windows has stopped.
All in all SuperDave I believe we have managed to cure it (or so it seems). 

Just because you have been cleaned of an infection, that doesn't always mean the work is over.

Do you think we need to go further or will we consider this as a successful outcome?

Many thanks for your assistance SuperDave. ImnoGuru

[SuperDave]

Ok, we can do some cleanup and we'll be done.

Download this program and run it Uninstall ComboFix .It will remove ComboFix for you.

Click Start> Computer> right click the C Drive and choose Properties> enter
Click Disk Cleanup from there.



Click OK on the Disk Cleanup Screen.
Click Yes on the Confirmation screen.



This runs the Disk Cleanup utility along with other selections if you have chosen any. (if you had a lot System Restore points, you will see a significant change in the free space in C drive)
************************************
Go to Microsoft Windows Update and get all critical updates.

----------

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[ImnoGuru]

Thanks for your help SuperDave.

Just finalized all the cleanup and I haven't had any interference or misdirections.
 All systems go here. In fact its probably the cleanest its ever been to be honest.

Many thanks for your guidance.

ImnoGuru 

[SuperDave]

You're welcome. I will lock this thread. If you need it re-opened, please send me a pm.