What Operating System are you using? This is a common problem with running newer software on Windows XP. Which programs are you trying to run?
If you are running Windows Vista or Later (Win8 according to your profile) start an admin command prompt and run sfc /scannow.
Don't do this. The best case scenario is things stay the same. More likely, you would make things far, far worse.
I runned sfc scannow and.. i got this message
begining system scan. this process will take time
i tried to open the cbs.log file it was in notepad. it said acess denied.
begining verification phase of system scan.
verification100% complete.
windows resourse protection found corrupt files but was unable to fix some of them.
details are included in the cbs.log windir\logs\CBS\CBS.log for example
C:\windows\logs\cbs\cbs.log
the system file repair changes will take effect after the next reboot.