I have Windows 10 Home laptop and a wireless MK320 Logitech keyboard and a wireless M310 Logitech mouse. Every time I would boot up I would have to go to settings and change the mouse to the Right Button for a Left handed use. Now, for the past few days the button will change itself back to Left without having been shut down. I do not have this problem with the wireless Logitech mouse I use with my Desk top computer. I have downloaded SetPoint from Logitech so I assume that should have been all I needed, but apparently not. Has anyone out there had the same problem and what did you do to correct it? Thank you...........