Forgot to mention. There are some issues that can arise with that motherboard.
The OP needs to try again with some peripherals disconnected. A high performance do-it-yourself system has some potential issues with peripherals, liker printers, external drives,cameras and stuff Ike that. Rare, but easy to check.
Such Bluetooth issues have been documented by Apple. Yeah, he does not have an Apple, but the 2.4 GHz inference issues are not limited to make of of computer.
https://support.apple.com/en-us/HT201542Potential sources of Wi-Fi and Bluetooth interference
Learn how to minimize wireless interference that can cause slower performance or disconnection from your Wi-Fi network and Bluetooth devices.
Not mentioned are wireless printers that have the potential to mess with Bluetooth.
I do hope this helps.