Download, install & update...
CLEANUP
Ccleaner
(During install, uncheck the Yahoo Toolbar option)
(After install, set Options>Advanced> 'Uncheck the 48 hour box')
ANTI SPYWARE
Ad-Aware
Spybot S&D
ANTI VIRUS
AVG Free (After install, set Options to 'scan all files')
ANTI TROJAN
EWIDO (W2k & XP Only)
and/or
A-Squared (aČ Winall)
Turn off System Restore if applicable. (ME & XP users)
Run Ccleaner
Run Ad-Aware
Run Spybot
Run AVG Free
Run Ewido and/or A-Squared (aČ)
Re-start in Safe Mode
Re-run AVG Free
Re-start in Normal Mode
Turn on System Restore if applicable. (ME & XP users)