I've been having this problem for months and I haven't been able to fix it. I went to the Microsoft site and tried to do what it said, but it didn't work. I have WindowsXP and every time I try to intall a certain game it gives me this error message:
C:\WINDOWS\SYSTEM32\CONFIG.NT. The system file is not suitable for running MS-DOS and Microsoft Windows applications. Choose 'Close' to terminate the application.