No, but three hard drives will consume more power. Coincedentally, that is was happened to me. I had C: and D: drives, both fairly small 2GB and 8GB, so I bought another 80GB drive. Yay! more space. Problem being that every once in a while it would simply vanish, causing some good old fashioned headaches because I had the swapfile on it.
As Patio suggested try another PSU for a while to see if the problems mysteriously dissapear. Personally I first suspected the PSU in my case when I reformatted to a new 160GB (replacing the C: and D: physical drives with a single, partitioned one).