Lol. I knew this would be the response.
I've never once had an issue with CCleaner cleaning the registry, or any other cleaner for that matter.
You guys go on about about how it will eventually screw up the system, but that has never been the case with me and I've been using PCs for quite some time.
You have to be smart about it, common sense wise, but what's wrong with removing traces in the registry of programs no longer installed?
Nothing, that's what.
I used CCleaner every day for almost 4 years on my last PC, cleaning everything, and no issues at all.
No blue screens, no warnings at starts, no re-boots, nothing.
I use it now on my new PC and if anything it keeps it just as fast as the day I bought it.
If four years doesn't mean a program works without doing harm, well, then it's too high a bar for any program to pass.
Do it intelligently, and no issues should arise.