Your symptoms are extremely vague, making real help difficult to provide.
The errors you are encountering would help, as they would point to the problem PHP is having.
I have zero experience with the product you mentioned, and next to no experience with my own PHP installs (I let Apache handle those things when I hosted my own, and now I let my hosting provider handle it). However, my gut instinct says that, since you're using IIS, it's a directory permission problem.
Either IIS isn't set up properly, or PHP doesn't have permissions to certain directories, or some effed up combination of those and a billion other things that could go wrong on a Windows install.
tl;dr: What are the errors you're getting?
-rock