You'll need brackets to securely mount that in any normal case. I don't think I've seen a case with 2.5" drive bays, only laptops. You could just lay it loose in there, but I don't suggest it.
Considering you could get a 2.5TB drive for that price, you're still wasting your money. You'd have over 62 times the space and you really wouldn't notice any different except maybe a few seconds faster in the OS loading. It won't make your computer or games or movies or anything else perform better.