It really depends on the level of infection and what the infections actually are. Unless you have a genuine interest in solving the problems that you'll come across, there comes a point when you have to balance the time spent in attempting to revive a system against the time saved on a fresh installation.
If you or your friend would like a stab at cleaning up this system, I'm sure you'll get all the help you need here.
Conversely, if you decide to bite the bullet and start again from scratch, I'm sure that help and advice for that will be available too.