System Idle Process is using 99... something... CPU units? I'll go with that. Everything else is using 0 U.
Interestingly, I have multiple copies of svchost.exe running. I believe this is the culprit. The memory usage for each is:
SYSTEM 4,076 K
LOCAL SERVICE 4,200 K
SYSTEM 19,428 k
NETWORK SERVICE 4,168 K
That highly spiked one worries me. The other big memory users are ISSVC.exe at 7,668 K, explorer.exe at 27,368 (HOLY S#!t!), CCAPP.EXE at... 24,356???, HOSTS_Secure.exe at 12,164, and firefox.exe at 30,600 K and climbing.
Interestingly, although my whole computer is laggy in Safe Mode (no video drivers active), it's not any slower than that when I click anything. I had a heck of a time getting Norton to scan, but it was relatively OK in Safe Mode.
OK, my exact symptoms, if there was any confusion: When I click something from Quick Launch, it waits about 5 seconds before loading. From the Start Menu, the Start menu doesn't disappear after I click until a few seconds later, then it's some more seconds before it loads the program.
So... what can I do? In safe mode, SpyBot found 6 other things and fixed them, everything else came up clean. And I don't think it's Norton, it was the first thing I installed and it's been working fine until now.