Try using GIANT Anti Spyware program. Its only a 15 day trial but it found and removed things that Spybot and Adaware could not find on my system. It saved me from having to reformat the drive and start clean again.
Its a great program IMO. I am most likely going to purchase it. Paying a little money is worth it to not have to reformat your drive twice a year to get rid of spyware/adware that no other programs will find/delete.