Sorry, I've been busy and I couldn't find any of my old PartitionMagic manuals. Plus, Google did not cooperate very well when I searched for information on DOS partition limitations, but I finally found a manual online. The following information is found on pages 38 & 39 of PartitionMagic 8.0 User Guide:
Creating Bootable Partitions:
Before creating a partition where you plan to install an operating system (a bootable
partition), you should understand the following information.
With the exception of DOS 6.22 (or earlier), partitions beyond 8 GB are visible to the current operating system. For more information, see “Understanding the BIOS 1,024 Cylinder (8 GB) Limit” and “Understanding the 2 GB Boot Code Boundary” in Help.
PartitionMagic 8.0 User GuideI don't currently have PartitionMagic installed, so I couldn't look at the Help, as suggested, but I believe this means that DOS 6.22 or earlier cannot see beyond 8GB & in order to be a bootable partition, the partition must reside within the first 2GB of the physical drive, so ... my memory was close, but ... not completely accurate.
Also, it may be that you need to put your DOS partition at the beginning of the drive in order to be bootable. (DOS had more limitations than newer OP systems, as you know) but I'm not sure that the location at the end of the physical drive would prevent DOS from seeing the drive.
If you want to boot DOS 6.22 on your HD, you will need to a tool such as PartitionMagic to resize and move your existing partitions, so that the FAT partition is at the beginning of the drive.
I have this suggestion:As an alternative, why not install DOS 6.22, or Windows 98SE DOS on a jump drive and boot with it when you want to run DOS. I have a couple of bootable jump drives with Windows 98SE DOS for that purpose. Is there any reason in particular that you need DOS 6.22? Windows 98SE DOS is very similar to DOS 6.22 as far as functionality, but has much higher limitations. IE: It has a Boot Boundary of 8 GB & can see either FAT or FAT32 partitions anywhere on very large HD drives. The Edit.com program is way better and able to handle much larger files. A bootable jump drive will save you a lot of trouble and get you pretty close to where you want to be! Also, go with 98SE DOS, if you can.