Get rid of the dbx files, Close windows not needed, buy more ram, increase the free space on the HD., empty all temp files, scan for a virus, run Malwarebytes, Clean your register, Get all the XP updates.
To compact and back up e-mail folders
1. Select an e-mail folder.
2. On the File menu, point to Folder, and then click Compact.
3. To back up the folder, find the folder file, and then copy it to a backup folder, floppy disk, or network drive. Outlook Express e-mail folders have a .dbx extension (for example, "Sent Items.dbx").
Notes
• Some message files might be too large to back up onto a floppy disk.
• If you are using a program other than Outlook Express to send e-mail messages to newsgroups, check your e-mail program's documentation for information about compacting and deleting e-mail folders.
After you back up the dbx file, delete the dbx files from the HD.