Well, I haven't installed a new drive in mine, but my old PC, a K6-2, BIOS date 1999, would freeze at the POST screen when trying to detect the large drive.
I was able to workaround it by setting a "cylinder reduction" jumper. Thing is I couldn't say wether the Toshiba will work with the drive, and if it didn't wether said drive would have this jumper
Information about the BIOS specs and so forth pertaining to the laptop is hard to find...