The disks contain x-rays and mri images, etc. The images are dicom formatted, commonly used in the medical field and the software that runs the app is called GEARView.
They do run automatically when inserted and I get the same error on both 32 and 64 bit machines. However, occasionally we will get a disk from the same hospital that will work fine, even though they are created by the same people, using the same version of software. I'm told that the disk are created on a Windows 7 PC as well.