What usually happens (and seems to only happen with two games, specifically 'Destiny 2' and 'Division 2') is I'll be in game and the screen will freeze, and then suddenly I'm back at the desktop (no blue screen). It usually happens after about 20 minutes of play. With Destiny there is no error message, it just drops me back on the desktop and the game closes. With Division I will occasionally get an error that the game has crashed (but not always).
It hasn't always happened, no. I upgraded my GPU and PSU a few months back and it seems to have started after that.
A friend suggested completely removing all graphics drivers using DDU but that process sounded a little scary, to be quite honest, at least on one particular walk-through I read.