I'd be weary of putting ALL my important files on one disk.
I'd probably lose the disk, or something similarly stupid. And knowing my luck, thats when I'd have a serious problem with the computer, heh.
Good idea, but I think storage capacity that high should be left for HDD's to take care of.
P.S. I bet in a few years that statement will sound crazy, there will probably be 1TB USB pens by that time, haha.