Lectrocrew, there is nothing at all wrong with your system or your components.
That is just a teensy little desktop tweak. Oh, boy. There are a few, and they are a bit different for Vista and XP. But you are basically simply losing your desktop icon settings back to their default position.
It might be a right-click on the desktop and then Personalize, somewhere. Or you might go to Kelly's Korner for a script to reset it. I'll post this now so you'll get it faster than I can research it out for you.
I've done it lots of times. I can absolutely assure you that one single keystroke is causing your worries. It is a totally "nothing" problem—er, once you know where the dickens that little setting is.
[Edit] My guess is the resolution shift is causing the icons to default their position, by the way.