RTS may refer to any of the following:
1. Short for request to send, RTS is a signal sent by a communications device, like a modem, to verify the other device is ready for data reception.
2. Short for real-time strategy, RTS is a computer game where actions occur immediately rather than giving each player a turn or waiting for an opponent to finish their action. Some examples of RTS games are Age of Empires, StarCraft, WarCraft.