1. In software, a frame is an edge or border that resembles a physical frame you would find around a picture. Frames are often used in word processing and graphic arts to help focus a viewer's attention.
2. In data or network communications, a frame is a data transmission unit with a header to indicate the beginning of a block of data and a trailer to indicate the end of it.
3. With a web page, a frame is a movable or non-movable portion of a web page that can make navigation easier and a way to bring other content from other sources into a page. A good example of this is the use of Internet advertising banners on a web page.
4. A frame is a single, still image displayed by the computer, video hardware, or software application and part of a larger sequence of images that make up a video or computer game. Also, see FPS and frame rate.