F Updated: 10/07/2019 by Computer Hope F may refer to any of the following: 1. F is an abbreviation for the F programming language. 2. F can be a drive letter in a computer, if the computer has multiple hard drives or hard drive partitions. 3. F is a key used with the keyboard shortcuts Alt+F and Ctrl+F. 4. F is the sixth letter of the English alphabet. See our F terms for a full listing of computer terms starting with "F."